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EC number: 235-008-5 | CAS number: 12054-48-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Well documented and acceptable publication
Data source
Reference
- Reference Type:
- publication
- Title:
- pH-DEPENDENT TOXICITY OF Cd, Cu, Ni, Pb AND Zn 10 CERIODAPHNIA DUBIA, PIMEPHALES PROMELAS, HYALELLA AZTECA AND LUMBRJCULUS VARIEGATUS
- Author:
- Schubauer-Berigan et al.
- Year:
- 1 993
- Bibliographic source:
- Envrionmental Toxicology and Chemistry. Vol. 12, Ptp. 1261-1266
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- no
Test material
- Reference substance name:
- Nickel dichloride
- EC Number:
- 231-743-0
- EC Name:
- Nickel dichloride
- Cas Number:
- 7718-54-9
- IUPAC Name:
- nickel(2+) dichloride
- Details on test material:
- - Name of test material (as cited in study report): Nickelchloride
Constituent 1
Test organisms
- Test organisms (species):
- Ceriodaphnia dubia
- Details on test organisms:
- TEST ORGANISM
- Common name: Water flea
- Source: Test organisms were cultured at the U.S. EPA laboratorys in Duluth, Minnesota
- Age at study initiation (mean and range, SD): < 48 h
- Feeding during test
- Food type: 100 µg of a yeast-Cerophyl (Agri-Tech, Kansas City,MO)-fermented Purina Brand (St. .Louis, MO)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 300 mg/L Ca CO3
- Test temperature:
- 25 °C
- pH:
- three pH values:
6.3, 7.3, 8.3 - Dissolved oxygen:
- never below 5 mg/L (60 % saturation)
- Details on test conditions:
- TEST SYSTEM
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 2-3
- No. of vessels per control (replicates): 2-3
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: reconstituted hard water
- Alkalinity: 225-245 mg/L CaCo3
OTHER TEST CONDITIONS
- Photoperiod: 16:8 light:dark cycle
- Adjustment of pH: yes, with HCL
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 0.2 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- element
- Remarks:
- Nickel
- Basis for effect:
- mortality
- Remarks on result:
- other: pH: 6.0-6.5
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.14 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- element
- Remarks:
- Nickel
- Basis for effect:
- mortality
- Remarks on result:
- other: pH: 7.0-7.5
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.013 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- element
- Remarks:
- Nickel
- Basis for effect:
- mortality
- Remarks on result:
- other: pH: 8.0-8.5
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 0.3 mg/L
- Conc. based on:
- other: Nickeldihydroxide
- Basis for effect:
- mortality
- Remarks on result:
- other: pH: 6.0-6.5. Result calculated for Nickeldihydroxide
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.22 mg/L
- Conc. based on:
- other: Nickeldihydroxide
- Basis for effect:
- mortality
- Remarks on result:
- other: pH: 7.0-7.5. Result calculated for Nickeldihydroxide
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.02 mg/L
- Conc. based on:
- other: Nickeldihydroxide
- Basis for effect:
- mortality
- Remarks on result:
- other: pH: 8.0-8.5. Result calculated for Nickeldihydroxide
Applicant's summary and conclusion
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