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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Peer reviewed data, acceptable for assessment.

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
SIDS Initial Assessment Profile on Nickel and Nickel Compounds-Draft SIAR
Author:
OECD
Year:
2007
Bibliographic source:
SIDS Dossier -Draft
Reference Type:
publication
Title:
Development and validation of biotic ligand models for predicting nickel toxicity to fish, daphnids and algae.
Author:
Deleebeeck, De Schamphelaere, Heijerick, Bossuyt & Janssen
Year:
2005
Bibliographic source:
University of Ghent. 150 p. cited in: SIDS

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 211 (Daphnia magna Reproduction Test)
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Nickel dichloride
EC Number:
231-743-0
EC Name:
Nickel dichloride
Cas Number:
7718-54-9
IUPAC Name:
nickel(2+) dichloride
Details on test material:
- Name of test material (as cited in study report): NiCl2
- Analytical purity: reagent grade

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Daphnia magna
Details on test organisms:
TEST ORGANISM
- Common name: water flea
- Source: Test organisms originated from a healthy clone (K6) of D. magna, which has been cultured under standardized
conditions in M4 medium for several years.
- Age of parental stock (mean and range, SD): < 24 h
- Feeding during test
- Food type: Animals were fed every day with an algal mix of P. subcapitata and Chlamydomonas reinhardtii in a 3:1 ratio
(on a cell number basis). Each organism received 8 x 10E6 cells per day in the first week, 16 x 10E6 cells
per day in the second week and 24 x 10E6 cells per day in the third week of exposure.

Study design

Test type:
semi-static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
21 d

Test conditions

Test temperature:
20 °C
Details on test conditions:
TEST SYSTEM
- Test vessel: polyethylene cups containing 50 ml of test medium
- Renewal rate of test solution (frequency): daily
- No. of organisms per vessel: 1
- No. of vessels per concentration (replicates): 10
- No. of vessels per control (replicates): 10

EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
Every day, parent mortality noted, and the number of produced juveniles counted.
Reference substance (positive control):
not specified

Results and discussion

Effect concentrationsopen allclose all
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.053 - 0.389 mg/L
Conc. based on:
element
Remarks:
Ni
Basis for effect:
mortality
Duration:
21 d
Dose descriptor:
EC10
Effect conc.:
0.033 - 0.444 mg/L
Conc. based on:
element
Remarks:
Ni
Basis for effect:
reproduction
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.08 - 0.61 mg/L
Conc. based on:
other: Nickeldihydroxid
Basis for effect:
mortality
Remarks on result:
other: result calculated for Nickeldihydroxid
Duration:
21 d
Dose descriptor:
EC10
Effect conc.:
0.051 - 0.7 mg/L
Conc. based on:
other: Nickeldihydroxid
Basis for effect:
reproduction
Remarks on result:
other: result calculated for Nickeldihydroxid

Applicant's summary and conclusion