Nickel dihydroxide

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

long-term toxicity to aquatic invertebrates

Type of information:

migrated information: read-across based on grouping of substances (category approach)

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Peer reviewed data, acceptable for assessment.

Data source

Reference

Reference 1

Reference Type:

secondary source

Title:

SIDS Initial Assessment Profile on Nickel and Nickel Compounds-Draft SIAR

Author:

OECD

Year:

2007

Bibliographic source:

SIDS Dossier -Draft

Reference 2

Reference Type:

publication

Title:

Development and validation of biotic ligand models for predicting nickel toxicity to fish, daphnids and algae.

Author:

Deleebeeck, De Schamphelaere, Heijerick, Bossuyt & Janssen

Year:

2005

Bibliographic source:

University of Ghent. 150 p. cited in: SIDS

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 211 (Daphnia magna Reproduction Test)

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

Nickel dichloride

EC Number:

231-743-0

EC Name:

Nickel dichloride

Cas Number:

7718-54-9

IUPAC Name:

nickel(2+) dichloride

Details on test material:

- Name of test material (as cited in study report): NiCl2
- Analytical purity: reagent grade

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

no

Test organisms

Test organisms (species):

Daphnia magna

Details on test organisms:

TEST ORGANISM
- Common name: water flea
- Source: Test organisms originated from a healthy clone (K6) of D. magna, which has been cultured under standardized
conditions in M4 medium for several years.
- Age of parental stock (mean and range, SD): < 24 h
- Feeding during test
- Food type: Animals were fed every day with an algal mix of P. subcapitata and Chlamydomonas reinhardtii in a 3:1 ratio
(on a cell number basis). Each organism received 8 x 10E6 cells per day in the first week, 16 x 10E6 cells
per day in the second week and 24 x 10E6 cells per day in the third week of exposure.

Study design

Test type:

semi-static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

21 d

Test conditions

Test temperature:

20 °C

Details on test conditions:

TEST SYSTEM
- Test vessel: polyethylene cups containing 50 ml of test medium
- Renewal rate of test solution (frequency): daily
- No. of organisms per vessel: 1
- No. of vessels per concentration (replicates): 10
- No. of vessels per control (replicates): 10

EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
Every day, parent mortality noted, and the number of produced juveniles counted.

Reference substance (positive control):

not specified

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

21 d

Dose descriptor:

NOEC

Effect conc.:

0.053 - 0.389 mg/L

Conc. based on:

element

Remarks:

Ni

Basis for effect:

mortality

Effect concentrations 2

Duration:

21 d

Dose descriptor:

EC10

Effect conc.:

0.033 - 0.444 mg/L

Conc. based on:

element

Remarks:

Ni

Basis for effect:

reproduction

Effect concentrations 3

Duration:

21 d

Dose descriptor:

NOEC

Effect conc.:

0.08 - 0.61 mg/L

Conc. based on:

other: Nickeldihydroxid

Basis for effect:

mortality

Remarks on result:

other: result calculated for Nickeldihydroxid

Effect concentrations 4

Duration:

21 d

Dose descriptor:

EC10

Effect conc.:

0.051 - 0.7 mg/L

Conc. based on:

other: Nickeldihydroxid

Basis for effect:

reproduction

Remarks on result:

other: result calculated for Nickeldihydroxid