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Diss Factsheets
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EC number: 235-008-5 | CAS number: 12054-48-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods: long-term
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable well documented publication.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Ecotoxicity of nickel to Eisenia fetida, Enchytraeus albidus and Folsomia candida.
- Author:
- Lock, K. and Janssen, C. R.
- Year:
- 2 002
- Bibliographic source:
- Chemosphere, 46, 197-200.
- Reference Type:
- secondary source
- Title:
- SIDS Initial Assessment Profile on Nickel and Nickel Compounds-Draft SIAR
- Author:
- OECD
- Year:
- 2 007
- Bibliographic source:
- SIDS Dossier -Draft
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- ISO 11268-2 (Effects of Pollutants on Earthworms. 2. Determination of Effects on Reproduction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
- Version / remarks:
- for the artificial soil
- GLP compliance:
- no
Test material
- Reference substance name:
- Nickel dichloride
- EC Number:
- 231-743-0
- EC Name:
- Nickel dichloride
- Cas Number:
- 7718-54-9
- IUPAC Name:
- nickel(2+) dichloride
- Details on test material:
- - Name of test material (as cited in study report): Nickelchloride (NiCl2)
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test organisms
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
- Details on test organisms:
- TEST ORGANISM
- Common name: earthworm
- Source: commercial earthworm farm, but all culures have been maintained in the laboratory for at least five years
Study design
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- no
- Total exposure duration:
- 3 wk
Test conditions
- Test temperature:
- 20 ± 1 °C
- pH:
- 6
- Details on test conditions:
-
SOURCE AND PROPERTIES OF SUBSTRATE (if soil)
- Composition (if artificial substrate): according to OECD 207; 70 % sand, 20 % kaolinclay and 10 % finely ground Spagnum peat.
OTHER TEST CONDITIONS
- Photoperiod: 16:8 light/dark cycle
- Light intensity: 400-800 lux - Nominal and measured concentrations:
- Nominal concentrations were 100, 180, 320, 560 and 1000 mg Ni/Kg dry wt.
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 3 wk
- Dose descriptor:
- NOEC
- Effect conc.:
- 180 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Remarks:
- Nickel
- Basis for effect:
- reproduction
- Duration:
- 3 wk
- Dose descriptor:
- EC50
- Effect conc.:
- 262 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Remarks:
- Nickel
- Basis for effect:
- reproduction
- Duration:
- 3 wk
- Dose descriptor:
- EC100
- Effect conc.:
- 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Remarks:
- Nickel
- Basis for effect:
- reproduction
- Duration:
- 3 wk
- Dose descriptor:
- NOEC
- Effect conc.:
- 284.3 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- other: Nickeldihydroxid
- Basis for effect:
- reproduction
- Remarks on result:
- other: Result calculated for Nickeldihydroxid
- Duration:
- 3 wk
- Dose descriptor:
- EC50
- Effect conc.:
- 413.86 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- other: Nickeldihydroxid
- Basis for effect:
- reproduction
- Remarks on result:
- other: Result calculated for Nickeldihydroxid
- Duration:
- 3 wk
- Dose descriptor:
- EC100
- Effect conc.:
- 1 579.6 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- other: Nickeldihydroxid
- Basis for effect:
- reproduction
- Remarks on result:
- other: Result calculated for Nickeldihydroxid
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.