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EC number: 204-881-4 | CAS number: 128-37-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- No guideline was followed and no GLP. However, it provides some scientific valid information for the weight of evidence analysis.
- Principles of method if other than guideline:
- Solubilites of BHT were determined either by a radiotracer technique for low concentrations or by visually observing the dissolution process as the temperature of a mixture is changed.
- GLP compliance:
- not specified
- Key result
- Medium:
- other: n-heptane
- Solubility:
- 55.9 other: wt %
- Temp.:
- 29.5 °C
- Key result
- Medium:
- ethanol
- Solubility:
- 34 other: wt %
- Temp.:
- 28.7 °C
- Key result
- Medium:
- n-octanol
- Solubility:
- 31.1 other: wt %
- Temp.:
- 29.5 °C
- Test substance stable:
- not determined
- Conclusions:
- The solubility of BHT in various solvents was measured as follows:
Solubility of BHT in n-heptane at 29.5 ºC is 55.9 wt%
Solubility of BHT in ethanol at 28.7 ºC is 34 wt%
Solubility of BHT in 1-octanol at 29.5 ºC is 31.1 wt% - Executive summary:
The solubility of BHT in various solvents was measured as follows:
Solubility of BHT in n-heptane at 29.5 ºC is 55.9 wt%
Solubility of BHT in ethanol at 28.7 ºC is 34 wt%
Solubility of BHT in 1-octanol at 29.5 ºC is 31.1 wt%
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- Peer reviewed data.
- Principles of method if other than guideline:
- No data provided on the test method.
- GLP compliance:
- not specified
- Conclusions:
- Freely soluble in toluene; soluble in methanol, isopropanol, methyl ethyl ketone, acetone, cellosolve, benzene, most hydrocarbon solvents, ethanol, petroleum ether, liquid petrolatum (white oil): 0.5% w/w; more soluble in food oils and fats than butylated hydroxyanisol; good solubility in linseed oil.
- Executive summary:
Freely soluble in toluene; soluble in methanol, isopropanol, methyl ethyl ketone, acetone, cellosolve, benzene, most hydrocarbon solvents, ethanol, petroleum ether, liquid petrolatum (white oil): 0.5% w/w; more soluble in food oils and fats than butylated hydroxyanisol; good solubility in linseed oil.
Referenceopen allclose all
Freely soluble in toluene; soluble in methanol, isopropanol, methyl ethyl ketone, acetone, cellosolve, benzene, most hydrocarbon solvents, ethanol, petroleum ether, liquid petrolatum (white oil): 0.5% w/w; more soluble in food oils and fats than butylated hydroxyanisol; good solubility in linseed oil.
Description of key information
Based on the data included in the handbook, BHT is freely soluble in toluene; soluble in methanol, isopropanol, methyl ethyl ketone, acetone, cellosolve, benzene, most hydrocarbon solvents, ethanol, petroleum ether, liquid petrolatum (white oil): 0.5% w/w; more soluble in food oils and fats than butylated hydroxyanisol; good solubility in linseed oil.
Based on the experimental results from the scientific article, the solubility of BHT in various solvents was measured as follows:
Solubility of BHT in n-heptane at 29.5 ºC is 55.9 wt%
Solubility of BHT in ethanol at 28.7 ºC is 34 wt%
Solubility of BHT in 1-octanol at 29.5 ºC is 31.1 wt%
Key value for chemical safety assessment
Additional information
Weight of evidence: Experimental results from a handbook and a scientific article.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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