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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

Long-term toxicity to fish is not expected

Key value for chemical safety assessment

Additional information

According to EC 1907/2006, Annex IX, Column 2, long term toxicity testing shall be proposed if the chemical safety assessment according to Annex I indicates the need to investigate further the effects on aquatic organisms. Amides, C16-C18 (even), N,N'-ethylenebis is highly insoluble in water, and therefore its bioavailability through this exposure route is limited. Moreover, the substance did not exert toxicity to any of the aquatic organisms used in the experimental studies available (acute toxicity to invertebrates, algae, microorganisms, and acute toxicity to fish), included Daphnia after 21 days of exposure (long term study). Since there is no indication that fish sensitivity would be greater than that of Daphnia, similar results for long term fish studies can be expected. Therefore, and in order to preserve animal welfare, further testing for this endpoint is not considered necessary.