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Ecotoxicological information

Long-term toxicity to fish

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Reference
Endpoint:
fish early-life stage toxicity
Data waiving:
other justification
Justification for data waiving:
other:

Description of key information

Long-term toxicity to fish is not expected

Key value for chemical safety assessment

Additional information

Studies on the chronic toxicity of the substance to fish are not available. The substance is insoluble in water and the available short-term toxicity studies for fish, daphnia and algae indicate no aquatic toxicity of the substance to aquatic organisms. The available chronic data for aquatic invertebrates (OECD 211) and algae (OECD 201) determined no chronic effects of the substance. Since there is no indication in the short-term tests that invertebrates are less sensitive than fish, it is unlikely that a long-term test with fish will generate different results than the available long-term study with aquatic invertebrates. The available study on the bioaccumulation potential of the substance in fish determined BCF values clearly < 2000 L/kg. Based on these considerations and in order to avoid unnecessary vertebrate testing for animal welfare reasons, no further long-term test with fish was proposed.

In summary, the chemical safety assessment carried out according to Annex I of Regulation (EC) No 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish. Thus, in accordance to Annex IX, column 2 no further long-term toxicity test to fish is proposed.