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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

Amides, C16-C18 (even), N,N'-ethylenebis is not readily biodegradable

Key value for chemical safety assessment

Additional information

Two studies investigating the ready biodegradability of Amides, C16-C18 (even), N,N'-ethylenebis were available. The report from Coenen (1991) was chosen as key study. This test was performed following the OECD Guideline No. 301B: Ready Biodegradability: Modified Sturm Test (1981), under GLP conditions. Activated sludge was used as inoculum and test material concentrations were 10 and 20 mg/L. On day 28 (end of the test) biodegradation values reached 15% and 5.5% at 10 and 20 mg/L test concentrations respectively. An additional supporting study was obtained from the Japanese Ministry of International Trade and Industry (MITI, 1976). This ready biodegradability test was carried out according to the OECD Guideline TG 301C: MITI (I), using activated sludge as inoculum at a concentration of 30 ppm. The test concentration used in the study was 100 ppm. After 14 days (end of the study), the test substance reached a biodegradation value of 1.1%. Thus, these results support those from the key study and Amides, C16-C18 (even), N,N'-ethylenebis can be considered as not readily biodegradable but the substance is hardly soluble in water and the very low solubility of the test substance may reduce the availability of the substance in the test medium.

Therefore, an additional calculation was used to investigate the biodegradation of  Amides, C16-C18 (even), N,N'-ethylenebis. A QSAR prediction using the following models Biowin1, Biowin2, Biowin3, Biowin4, Biowin5, Biowin6 and Biowin7

shows that the substance is not persistent in the environment and the biodegradation takes place in a time frame of weeks (Knoell Consult, 2010).