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Short-term toxicity to fish

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Description of key information

Amides, C16-C18 (even), N,N'-ethylenebis exhibited no acute toxicity to fish 

Key value for chemical safety assessment

Additional information

Two studies investigating the acute toxicity of Amides, C16-C18 (even), N,N'-ethylenebis to two different fish species were available. A report from the Japanese Ministry of Environment (MOE, 2002) was chosen as key study. This test was conducted according to OECD Guideline No. 203: Fish, acute toxicity test (1992), using Oryzias latipes as test organism. The results from this study show that after 96 hours exposure to the test substance, no effects were observed up to the highest attainable concentration (0.027 mg/L, limit of solubility). Therefore, the 96-h LC50 was greater than 0.027 mg/L, and no toxicity within the range of water solubility was reported. The test from the supporting study (Bürger and Heyner, 2002), was carried out according to OECD Guideline No. 203: Fish, acute toxicity test (1992), using Brachydanio rerio (Danio rerio) as test organism, under static conditions. Four nominal test concentrations were used, 10, 100, 1000 and 10000 mg/L, and mortality reported after 24, 48, 72 and 96 hours. At the end of the test (96 hours) no mortality was observed up to the highest concentration tested. Therefore, the 96h EC50 was greater than 10000 mg/L. Additional information was collected from the Japanese Ministry of International Trade and Industry (MITI, 1988), regarding a 48 hour test in which N,N’-ethane-1,2 diyldioctadecanamide did not have an effect on Oryzias latipes, being the 48h-LC50 greater than 300 mg/L (nominal concentration).

 

In conclusion, Amides, C16-C18 (even), N,N'-ethylenebis exhibited no acute toxicity to fish.