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Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Link to relevant study record(s)

Description of key information

A number of studies are available that show the substance is readily biodegradable, both as a whole and the individual alkyl dimethylamine oxide constituents.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

In the key study [Clarke (2005)] the ready biodegradability of the substance was assessed according to OECD TG 301 B (CO2 evolution test) under GLP. 90 % degradation (based on CO2 evolution) was observed after 28 days when the inoculum (domestic activated sludge) was treated with the substance at a concentration of 10 mg C/L. The test was performed in duplicate. The substance reached 42 % degradation on Day 2 and 72 % on Day 8, hence meeting the 10 day window requirement for ready biodegradability. The reference substance, sodium benzoate, reached 29 % biodegradation at Day 1 and 61 % at Day 2, meeting the validity criteria established in the guideline for a reference substance.

Several supporting studies where the substance was tested to OECD TG 301 B [Casteel (2007)] [Hirschen (2001)], OECD TG 301 D [Balk & Hantink-De Rooij (1987)] or DIN 38 409 H 41 [Klein (1986)] are available. The substance was found to be readily biodegradable in all of these studies. Casteel (2007) also reports the results of OECD TG 301 B studies performed using the individual alkyl dimethylamine oxide constituents (from C10 -C16). Each of these constituents was found to be readily biodegradable, meeting the 10 day window.