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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Qualifier:
no guideline followed
Principles of method if other than guideline:
The amine oxides were synthesised by oxidation of the corresponding trialkylamine with H2O2. After oxidation and isolation the products were thoroughly dried by azeotropic distillation with benzene and toluene followed by multiple crystallisations (4-5 times) from dry Me2CO and dried over P4O10 in a high vacuum. The purity was checked by TLC and IR spectra.
GLP compliance:
no
Type of method:
other: method not specified, however a capillary method was used for shorter chain length amine oxides
Melting / freezing pt.:
133 - 136 °C
Atm. press.:
1 013 hPa
Remarks on result:
other: C10 AO
Melting / freezing pt.:
130 - 134 °C
Atm. press.:
1 013 hPa
Remarks on result:
other: C12 AO
Melting / freezing pt.:
125 - 129 °C
Atm. press.:
1 013 hPa
Remarks on result:
other: C14 AO
Melting / freezing pt.:
126 - 130 °C
Atm. press.:
1 013 hPa
Remarks on result:
other: C16 AO

A study is described in the literature [Devinsky et al 1985] where the authors measured the melting points of the pure alkyl dimethylamine oxide constituents of the substance. The melting points ranged from 126-130 °C for C16 amine oxide to 133-136 °C for C10 amine oxide. Based on these values the melting point of the substance is expected to be in the range of 125 -136 °C.

Conclusions:
Based on the experimental melting points of the different alkyl chain length components, the melting point of the substance is approximately 126-136

Description of key information

Based on the melting points of the pure alkyl dimethylamine oxides, the melting point is expected to be in the range of 125-136 °C

Key value for chemical safety assessment

Additional information

A study is described in the literature [Devinsky et al 1985] where the authors measured the melting points of the pure alkyl dimethylamine oxide constituents of the substance. The melting points ranged from 126-130 °C for C16 amine oxide to 133-136 °C for C10 amine oxide. Based on these values the melting point of the substance is expected to be in the range of 126 -136 °C.