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Long-term toxicity to fish

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Link to relevant study record(s)

Description of key information

One long term (302 days) toxicity to fish study is available. No effect concentration of 0.42 mg AO/L was reported in the study.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
0.42 mg/L

Additional information

In a full life-cycle toxicity test (similar to EPA OPPTS 850.1500) fathead minnows (Pimephales promelas) were exposed to the substance for 302 days under flow through conditions [Aquatic Environmental Services (1976)]. The nominal test concentrations were 0, 0.06, 0.13, 0.25, 0.50, and 1.0 mg AO/L . Mean measured concentrations were 82 -117% of nominal. Endpoints included survival, growth, and hatchability. The NOEC was 0.42 mg AO/L (mean measured concentration), based on reduced fry survival, reduced egg hatch, and occluded eyes in test fish. This was consistent with results of a preliminary 15 -day test, in which the NOEC was 0.495 mg AO/L.