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Diss Factsheets
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EC number: 203-005-8 | CAS number: 102-09-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Principles of method if other than guideline:
- Direct method
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- 3.28
- Remarks on result:
- other: no information on temperature or pH
- Conclusions:
- The measured partition coefficient of diphenyl carbonate is 3.28.
Uncertainty due to hydrolysis of the substance (t 1/2 = 40 hours). - Executive summary:
The measured partition coefficient of diphenyl carbonate is 3.28.
Uncertainty due to hydrolysis of the substance (t 1/2 = 40 hours).
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Principles of method if other than guideline:
- Microemulsion electrokinetic chromatography (MEEKC) is an capillary electrophoretic technique in which a microemulsion is used as carrier electrolyte.
- GLP compliance:
- not specified
- Type of method:
- other: Microemulsion electrokinetic chromatography
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- 3.21
- Temp.:
- 25 °C
- pH:
- 7.4
- Conclusions:
- The measured partition coefficient of diphenyl carbonate is 3.21 at 25 °C at pH 7.4.
Uncertainty due to hydrolysis of the substance (t 1/2 = 40 hours). - Executive summary:
The measured partition coefficient of diphenyl carbonate is 3.21 at 25 °C at pH 7.4.
Uncertainty due to hydrolysis of the substance (t 1/2 = 40 hours).
Referenceopen allclose all
Uncertainty due to hydrolysis of the substance (t 1/2 = 40 hours)
At pH 7.4 a log Pow of 3.21 is obtained.
Uncertainity of the result due to hydrolysis (t 1/2 = 40 hours).
Description of key information
The Partition coefficient of diphenyl carbonate has been determined to be: 3.28, Direct method, Hansch (1995); 3.21 at 25.0 °C, Micro-emulsion electro-kinetic chromatography, Ostergaard et al. (2003)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 3.21
- at the temperature of:
- 25 °C
Additional information
This endpoint has been addressed with two key studies. Both studies were awarded a reliability score of 2 in accordance with the criteria for assessing data quality as set forth by Klimisch et al. (1997). However both data sources state that there is some uncertainty due to hydrolysis of the substance (t 1/2 = 40 hours).
The first value was taken from the publication titled “Exploring QSAR, Hydrophobic, Electronic, and Steric Constants” from ACS Professional Reference Book (Hansch, 1995). This data source identifies the low Pow (octanol-water) of diphenyl carbonate as 3.28 calculated using the direct method (temperature and pH were not reported).
The second value provided was sourced from the publication “Determination of octanol-water partition coefficients for carbonate esters and other small organic molecules by micro-emulsion electro-kinetic chromatography” (Ostergaard et al., 2003). The log Pow was identified as 3.21 at 25 °C at pH 7.4. using a capillary electrophoretic technique in which a microemulsion is used as carrier electrolyte.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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