Registration Dossier
Registration Dossier
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EC number: 931-700-2 | CAS number: 66455-29-6
Health surveillance data
Administrative data
- Endpoint:
- health surveillance data
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study meets generally accepted scientific principles, acceptable for assessment. Medical surveillance data.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 009
Materials and methods
- Study type:
- medical monitoring
- Endpoint addressed:
- skin irritation / corrosion
- eye irritation
- respiratory irritation
- skin sensitisation
- Principles of method if other than guideline:
- Routine medical check up of workers involved in production of the test substance.
- GLP compliance:
- no
Test material
- Reference substance name:
- (carboxylatomethyl)dodecyldimethylammonium
- EC Number:
- 211-669-5
- EC Name:
- (carboxylatomethyl)dodecyldimethylammonium
- Cas Number:
- 683-10-3
- Molecular formula:
- C16H33NO2
- IUPAC Name:
- [dodecyl(dimethyl)ammonio]acetate
- Reference substance name:
- Cocoyl dimethyl betaine
- IUPAC Name:
- Cocoyl dimethyl betaine
- Test material form:
- other: not applicable
- Details on test material:
- - Name of test material (as cited in study report): Cocoyl dimethyl betaine (INCI: Coco Betaine, NAS no. 683-10-3
- Analytical purity: not specified
Constituent 1
Constituent 2
Method
- Type of population:
- occupational
- Ethical approval:
- not applicable
- Details on study design:
- Routine medical check up of 25 workers of a production plant, examined by occupational medicine department every 3 years. The last check up was carried out in 2009. Workers were examined for disorders like irritation of the respiratory tract, the eyes, skin, allergic disorders or sensitisation related to contact with the test substance.
Results and discussion
- Results:
- During these examinations no observations of disorders such as irritation of the respiratory tract, the eyes, the skin, allergic reactions or sensitisation have been made, which were related to the test substance.
Any other information on results incl. tables
Conclusion:
The test substance does induce irritating or sensitising effects in workers involved in the production of the substance.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
