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Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1976
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
The study was performed before OECD test guidelines and GLP were established. The documentation is according to the best practice at the time the study was performed. However, some critical details of the test protocol and the results are not available.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1976
Report date:
1976

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
BASF test
GLP compliance:
no
Remarks:
Pre-GLP

Test material

Constituent 1
Chemical structure
Reference substance name:
2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs.
EC Number:
308-760-8
EC Name:
2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs.
Cas Number:
98246-87-8
Molecular formula:
C32H60O2 / C34H64O2 / C36H68O2
IUPAC Name:
4-(C15-C17) alkylidene-3-(C14-​16)​ alkyloxetan-2one
Details on test material:
Attached to the oxetane ring there is a C14 or C16 alkyl group in the 3-position and a C15 or C17 alkylidene group in the 4-position. The appropriate EC number for this substance is EC 308-760-8 (EC name: 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs.)
Specific details on test material used for the study:
Test substance: other TS: Stearyldiketen TV 194/37

An AKD manufactured using a stearic acid rich blend of palmitic and stearic fatty acids.

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
olive oil
Doses:
no data
No. of animals per sex per dose:
no data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 6 800 mg/kg bw

Any other information on results incl. tables

Clinical signs: Dyspnoe, Apathy, slow movement. Gross pathology: no signs of treatement.

Applicant's summary and conclusion

Conclusions:
Limited reporting interpretaion is not possible.