Sodium chlorate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2004

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Study was carried out according to generally valid and internationally accepted testing guidelines and under GLP. The substance is considered to be adequately characterised. Therefore full validation applies.

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

Cited as Directive 92/69/EEC, A.6

Deviations:

no

GLP compliance:

yes

Type of method:

flask method

Key result

Water solubility:

ca. 717 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

1 000 g/L

Incubation duration:

>= 48 - <= 96 h

Temp.:

20 °C

pH:

> 4.49 - < 4.58

Remarks on result:

other:

Remarks:

Mean value of 6 determinations (3 replicates and 2 dilutions for each of them) between 627 and 789 g/L (RSD = 9%)

Water solubility:

ca. 736 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

1 000 g/L

Incubation duration:

>= 48 - <= 96 h

Temp.:

20 °C

pH:

> 4.74 - < 4.82

Remarks on result:

other:

Remarks:

Mean value of 6 determinations (3 replicates and 2 dilutions for each of them) between 663 and 874 g/L (RSD = 11%)

Water solubility:

ca. 696 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

1 000 g/L

Incubation duration:

>= 48 - <= 96 h

Temp.:

20 °C

pH:

> 8.64 - < 8.7

Remarks on result:

other:

Remarks:

Mean value of 6 determinations (3 replicates and 2 dilutions for each of them) between 650 and 735 g/L (RSD = 4%)

The test was performed at 20.0 +/- 0.5  C, in vessels protected from light.


    
    
    

Conclusion:In Milli-Q water, 717 +/-  65 g/L with a precision of 9 % and measured pH ranged from 4.49 to 4.58
In buffer pH 6, 736 +/- 79 g/L with a precision of 11 % and measured pH ranged from 4.74 to 4.82
In buffer pH 9, 696 +/- 31 g/L with a precision of 4 % and measured pH ranged from 8.64 to 8.70.







  
  
  

No statistical difference was found in the stability of the test item, when tested in pH's from 4.49 to 8.70

Conclusions:

The water solubility of test item was found to be between 696 g/L and 736 g/L at 20°C for pH's ranging from 4.49 to 8.70.
A mean value of 717 g/L, corresponding to the water solubility of test item obtained in Milli-Q water, was considered as key data.

Executive summary:

The water solubility of test item was determined acccording to EU method A.6 based on the flask method and under GLP.

A mean value of 717 g/L at 20°C, corresponding to the water solubility of test item obtained in Milli-Q water, was considered as key data.

Description of key information

A fully reliable experimental study, conducted according to a recognized EC method and under GLP, is available. It is considered as a key study.

Water solubility of test item : 696-736 g/L at 20°C for pH 4.49 to 8.70.

A mean value of 717 g/L, corresponding to the water solubility of test item obtained in Milli-Q water, was considered as key data.

Key value for chemical safety assessment

Water solubility:

717 000 mg/L

at the temperature of:

20 °C

Additional information

A fully reliable experimental study, conducted according to a recognized EC method and under GLP, is available.

The water solubility of test item was found to be between 696 g/L and 736 g/L at 20°C for pH's ranging from 4.49 to 8.70.

A mean value of 717 g/L, corresponding to the water solubility of test item obtained in Milli-Q water, was considered as key data.