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Physical & Chemical properties

Vapour pressure

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Description of key information

The isothermal thermogravimetric effusion method (in accordance with EC A.4, OECD 104 and GLP) was performed but did not result in a value for the vapour pressure due to thermal decomposition.  Using EPI Suite MPBPWIN v1.43, the vapour pressure of tetramethylammonium hydroxide was predicted to be 1.54x10^-4 Pa (modified Grain method). 

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

Weight of evidence approach:

- During the performance of the isothermal thermogravimetric effusion method no vapour pressure could be determined for tetramethylammonium hydroxide pentahydrate. During heating, evaporation of water was observed followed by reaction/decomposition and subsequent evaporation of the degradation products.

- Using EPI Suite MPBPWIN v1.43, the vapour pressure of tetramethylammonium hydroxide was predicted to be 1.54x10^-4 Pa (modified Grain method).

- Using EPI Suite MPBPWIN v1.41, the vapour pressure of tetramethylammonium hydroxide was predicted to be 1.55x10^-4 Pa (data taken from OECD SIDS Initial Assessment report for SIAM 22).

- EPI Suite MPBPWIN is a known calculation tool for screening this end point.

 

Calculation with MPBPWIN v1.43 resulted in a low vapour pressure as was expected for a solid salt like tetramethylammonium hydroxide.The value given in the OECD SIDS (peer-reviewed) confirmed this low value. The value calculated with the most recent program, MPBPWIN v1.43, was reported as key value.