Registration Dossier

Administrative data

Link to relevant study record(s)

Description of key information

no studies available.
to estimate the toxicokinetics properties of the substance, physicochemical parameters are utilised (Regulation (EC) No 1907/2006, Annex VII, 8.8.1).

Key value for chemical safety assessment

Bioaccumulation potential:
low bioaccumulation potential
Absorption rate - oral (%):
100
Absorption rate - dermal (%):
100
Absorption rate - inhalation (%):
10

Additional information

physicochemical parameters used for toxicokinetic Endpoint summary:

Parameter

Value used for CSR

Molecular weight

133.15 g/mol

Melting point

84 - 87 °C

Boiling point

> 350 °C (at 1.1013 hPa)

Density

1.13 g/cm3(at 100 °C)

Vapour pressure

0.004 kPa (at 20 °C)

Partition coefficient n-octanol/water (log POW)

1.08 (at 25 °C)

Water solubility

4 g/L (at 25 °C)

pH

5 - 6

pKa

8.85 (at 25 °C)

Particle size

> 1400 µm

Based on these parameters, the bioaccumulation potential is judged as low (log POW< 4)

The substance is a solid with a high boiling point and a low Vapour pressure, the particle size is large,

which leads to a low absorption rate by inhalation.

For dermal and oral Absorption rate 100 % are assumed by default.