Registration Dossier

Toxicological information

Toxicity to reproduction

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Administrative data

Endpoint:
multi-generation reproductive toxicity
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study

Data source

Reference
Reference Type:
publication
Title:
Amino acids from chemical group 34 Flavouring Group Evaluation 26, Revision 1 Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) (Question No EFSA-Q-2003-169B)
Author:
EFSA
Year:
2008
Bibliographic source:
EFSA Journal (2008), 790: 1-51

Materials and methods

Results and discussion

Applicant's summary and conclusion

Conclusions:
A dose level of 3500 ppm L-cysteine in the diet of rats, equivalent to approximately 175 mg/kg bw/day, did not result in any adverse effects on reproduction over six generations.