Registration Dossier

Classification & Labelling & PBT assessment

GHS

General Information

Name:
4-nitro-o-anisidine
Implementation:
EU
Remarks:
The substance is self-classified as R40 (DSD) corresponding to H351 (GHS) derived from tumor formation in a feeding test of rats with the structural isomer 2-methoxy-5-nitroaniline (Lit. Berufsgenossenschaft der Chemischen Industrie, issue 12/95).

Related composition

Related composition:
Composition 2

Classificationopen allclose all

Explosives
Reason for no classification:
conclusive but not sufficient for classification
Flammable gases and chemically unstable gases
Reason for no classification:
data lacking
Aerosols
Reason for no classification:
data lacking
Oxidising gases
Reason for no classification:
data lacking
Gases under pressure
Reason for no classification:
data lacking
Flammable liquids
Reason for no classification:
data lacking
Flammable solids
Reason for no classification:
conclusive but not sufficient for classification
Self-reactive substances and mixtures
Reason for no classification:
conclusive but not sufficient for classification
Pyrophoric liquids
Reason for no classification:
data lacking
Pyrophoric solids
Reason for no classification:
data lacking
Self-heating substances and mixtures
Reason for no classification:
conclusive but not sufficient for classification
Substances and mixtures which in contact with water emit flammable gases
Reason for no classification:
data lacking
Oxidising liquids
Reason for no classification:
data lacking
Oxidising solids
Reason for no classification:
conclusive but not sufficient for classification
Organic peroxides
Reason for no classification:
data lacking
Corrosive to metals
Reason for no classification:
data lacking
Desensitized explosives
Reason for no classification:
data lacking
Acute toxicity - oral
Hazard category:
Acute Tox. 4
Hazard statement:
H302: Harmful if swallowed.
Acute toxicity - dermal
Reason for no classification:
conclusive but not sufficient for classification
Acute toxicity - inhalation
Reason for no classification:
data lacking
Skin corrosion / irritation
Reason for no classification:
conclusive but not sufficient for classification
Serious eye damage / eye irritation
Reason for no classification:
conclusive but not sufficient for classification
Respiratory sensitisation
Reason for no classification:
data lacking
Skin sensitisation
Reason for no classification:
conclusive but not sufficient for classification
Aspiration hazard
Reason for no classification:
data lacking
Reproductive toxicity
Reason for no classification:
data lacking
Effects on or via lactation
Reason for no classification:
data lacking
Germ cell mutagenicity
Reason for no classification:
data lacking
Carcinogenicity
Hazard category:
Carc. 2
Hazard statement:
H351: Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routs of exposure cause the hazard>.
Route of exposure:
Oral
1. Specific target organ toxicity - single
Reason for no classification:
inconclusive
1. Specific target organ toxicity - repeated
Reason for no classification:
data lacking
Hazardous to the aquatic environment (acute / short-term)
Reason for no classification:
data lacking
Hazardous to the aquatic environment (long-term)
Hazard category:
Aquatic Chronic 2
Hazard statement:
H411: Toxic to aquatic life with long lasting effects.
Hazardous to the ozone layer
Reason for no classification:
data lacking

Labelling

Signal word:
Warning

Hazard pictogram

GHS08: health hazard
GHS07: exclamation mark
GHS09: environment

Hazard statements

H302: Harmful if swallowed.
H351: Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routs of exposure cause the hazard>.
H411: Toxic to aquatic life with long lasting effects.

Precautionary statements

P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P264: Wash ... thoroughly after handling.
Specified precautionary statement P264.3: Wash skin thoroughly after handling
P273: Avoid release to the environment.
P281: Use personal protective equipment as required.
P308+P313: IF exposed or concerned: Get medical advice/attention.

Notes