Registration Dossier

Administrative data

Description of key information

4-Nitro-2-methoxy aniline was tested for skin and eye irritation in rabbits in several studies according to OECD guidelines.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Rabbits did not show signs of local irritation when treated with 4 -nitro-2 -methoxy aniline. Neither the dorsal skin nor the eyes reacted with erythema or edema. The minimal effects were confined to 1 of 3 animals on the skin. Ocular treatment caused minimal effects in the conjunctivae of most animals.

Justification for classification or non-classification

No signs of irritation detected.