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Solubility in organic solvents / fat solubility

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Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Justification for type of information:
Data is from experimental study reports
Qualifier:
according to
Guideline:
other: as mention below
Principles of method if other than guideline:
Weight of the chemical substance (fat) to dissolve in Organic Solvent to form a homogeneous solution of the solute in the solvent
GLP compliance:
no
Key result
Medium:
acetonitrile
Solubility:
> 1 000 g/L
Remarks on result:
other: VERY SOLUBLE
Key result
Medium:
dimethylformamide
Solubility:
> 1 000 g/L
Remarks on result:
other: VERY SOLUBLE
Key result
Medium:
methanol
Solubility:
> 1 000 g/L
Remarks on result:
other: VERY SOLUBLE
Key result
Medium:
toluene
Solubility:
> 1 000 g/L
Remarks on result:
other: VERY SOLUBLE
Test substance stable:
yes
Conclusions:
The solubility determination of test substance in various organic solvents was done with  acetonitrile, methanol,toluene and Dimethylformamide (DMF). The solubility of the test substance in acetonitrile, methanol, toluene and DMF was determine to be greater than 1000 g/l.
Executive summary:

The solubility determination of test substance in various organic solvents was done with  acetonitrile, methanol,toluene and Dimethylformamide (DMF). The solubility of the test substance in acetonitrile, methanol, toluene and DMF was determine to be greater than 1000 g/l.

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Justification for type of information:
Data is from experimental study report
Qualifier:
according to
Guideline:
other: Soxhlet/Solvent extraction method
Principles of method if other than guideline:
Weight of the chemical substance (fat) to dissolve in Organic Solvent to form a homogeneous solution of the solute in the solvent
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Key result
Medium:
other: Petroleum ether
Solubility:
1 000 000 mg/L
Temp.:
35 °C
Remarks on result:
other: very soluble
Test substance stable:
yes
Conclusions:
The solubility of test chemical in petroleum ether is determine to be 1000000 mg/L at 35 ºC by using Soxhlet/Solvent extraction method.This value indicates that test chemical is very soluble in petroleum ether.
Executive summary:

The solubility of test chemical in petroleum ether is determine to be 1000000 mg/L at 35 ºC by using Soxhlet/Solvent extraction method.This value indicates that test chemical is very soluble in petroleum ether.

Description of key information

The solubility determination of test substance in various organic solvents was done with  acetonitrile, methanol,toluene and Dimethylformamide (DMF). The solubility of the test substance in acetonitrile, methanol, toluene and DMF was determine to be greater than 1000 g/l.

The solubility of test chemical in petroleum ether is determine to be 1000000 mg/L at 35 ºC by using Soxhlet/Solvent extraction method.This value indicates that test chemical is very soluble in petroleum ether.

Key value for chemical safety assessment

Solubility in organic solvents at 20°C:
1 000 g/L

Additional information

The solubility determination of test substance in various organic solvents was done with  acetonitrile, methanol,toluene and Dimethylformamide (DMF). The solubility of the test substance in acetonitrile, methanol, toluene and DMF was determine to be greater than 1000 g/l.

The solubility of test chemical in petroleum ether is determine to be 1000000 mg/L at 35 ºC by using Soxhlet/Solvent extraction method.This value indicates that test chemical is very soluble in petroleum ether.