Registration Dossier
Registration Dossier
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EC number: 201-928-0 | CAS number: 89-65-6
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Final Report on the Safety Assessment of Ascorbyl Palmitate, Ascorbyl Dipalmitate, Ascorbyl Stearate,Erythorbic Acid, and sodium Erythorbate
- Author:
- F. Alan Andersen
- Year:
- 1 999
- Bibliographic source:
- International Journal of Toxicology
Materials and methods
- Principles of method if other than guideline:
- No guideline available. However, this substance has been fully evaluated by JECFA. And the data was also reviewed by peers.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,3-didehydro-D-erythro-hexono-1,4-lactone
- EC Number:
- 201-928-0
- EC Name:
- 2,3-didehydro-D-erythro-hexono-1,4-lactone
- Cas Number:
- 89-65-6
- Molecular formula:
- C6H8O6
- IUPAC Name:
- (5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one
Constituent 1
Test animals
- Species:
- rat
- Sex:
- male
Administration / exposure
- Route of administration:
- oral: feed
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- 18 000 mg/kg bw
- Based on:
- not specified
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
