Registration Dossier
Registration Dossier
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EC number: 216-613-3 | CAS number: 1624-62-0
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 4.58
- Temp.:
- 25 °C
- Remarks on result:
- other: no pH reported
- Conclusions:
- The logPow of Estron-Methylether was determined as 4.58.
- Executive summary:
The n-octanl/water partition coefficient of Estron-Methylether was determined with the HPLC-method according to OECD guideline 117 to be log Pow = 4.58. This method is based on the correlation of the reversed phase retention data of the test compound with those of reference compounds with known log Pow values.
Reference
Description of key information
The n-octanl/water partition coefficient of Estron-Methylether was determined with the HPLC-method according to OECD guideline 117 to be log Pow = 4.58. This method is based on the correlation of the reversed phase retention data of the test compound with those of reference compounds with known log Pow values.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.58
- at the temperature of:
- 25 °C
Additional information
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