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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Type of method:
effusion method: vapour pressure balance
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Temp.:
25 °C
Vapour pressure:
0 Pa
Temp.:
30 °C
Vapour pressure:
0 Pa

The temperature dependence of the vapour pressure was calculated from a regression straight line which is based on the Antoine relationship.

Conclusions:
The vapour pressure of Estron-Methylether at 25 °C was determined as 1.1E-5Pa.
Executive summary:

A study was conducted in accordance to guidance A.4 of the European Community to determine the vapour pressure of Estron-Methylether.

The vapour pressure of the test item was measured with a vapour pressure balance corresponding to the Knudsen effusion method. For measurement, the vapour jet of the test substance leaving a heatable Knudsen cell through an aperture of known size under high vacuum conditions is condensed on the cooled scale pan of a precision Cahn-microbalance. The evaporation rate is determined from the increase in weight per unit time from which the vapour pressure is calculated.

The temperature dependence of the vapour pressure was calculated from a regression straight line which is based on the Antoine relationship. The vapour pressure of Estron-Methylether at 25 °C was determined as 1.1E-5Pa.

Description of key information

A study was conducted in accordance to guidance A.4 of the European Community to determine the vapour pressure of Estron-Methylether.

The vapour pressure of the test item was measured with a vapour pressure balance corresponding to the Knudsen effusion method. For measurement, the vapour jet of the test substance leaving a heatable Knudsen cell through an aperture of known size under high vacuum conditions is condensed on the cooled scale pan of a precision Cahn-microbalance. The evaporation rate is determined from the increase in weight per unit time from which the vapour pressure is calculated.

The temperature dependence of the vapour pressure was calculated from a regression straight line which is based on the Antoine relationship. The vapour pressure of Estron-Methylether at 25 °C was determined as 1.1E-5Pa.


Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information