Registration Dossier
Registration Dossier
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EC number: 200-935-6 | CAS number: 76-12-0
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Absorption, distribution, metabolism and excretion of 1,1,2,2 -tetrachloro-1,2 –difluoroethane are discussed under the ACGIH sheet for the substance.
The American Conference of Governmental Industrial Hygienists(ACGIH) is a professional association of industrial hygienists and practitioners of related professions. One of the goals of the association is to provide information and guideline on exposure limits of substances in order to advance worker protection, and to this purpose the available scientific data on substances are revised.
ACGIH summaries are based on a review of existing peer-reviewed scientific literature by committees of experts in public health and related sciences, therefore ACGIH is considered a reliable secondary source of information.
According to the reference, chlorofluorocarbons as 1,1,2,2 -tetrachloro-1,2 –difluoroethane, appear to be eliminated almost exclusively through the respiratory tract. Little, if any, chlorofluorocarbon or metabolite has ever been reported in urine and feces. 1,1,2,2 -tetrachloro-1,2 –difluoroethane is absorbed by the lung and undergoes little, if any, significant biotransformation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
