Registration Dossier

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: not personal measurements, but results of stationary measurements on the workplace

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Test material

Reference
Name:
Unnamed
Type:
Constituent

Method

Ethical approval:
not applicable
Details on study design:
During Turn Around activities at the DAB-fabriek the installation is opened up for maintenance activities.
During these maintenance activities potential exposure to1,4-di aminobutane (DAB) has been measured (local, stationary measurements in the air).
Exposure assessment:
measured

Results and discussion

Results:
All but one measurement were below the analytical detection level (0.01-0.03 mg/m3).
One measurement =0.03 mg/m3

Applicant's summary and conclusion

Conclusions:
All but one measurement were below the analytical detection level (0.01-0.03 mg/m3).
One measurement =0.03 mg/m3
These concentrations measured in areas where people work, are fare below the DNEL (7 mg/m3).
Executive summary:

During a turn around (maintenace activities) at the DAB plant, stationary measurements in air were performed.

All but one measurement were below the analytical detection level (0.01-0.03 mg/m3).

One measurement =0.03 mg/m3

These concentrations measured in areas where people work, are fare below the DNEL (7 mg/m3).