Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
dissociation constant
Type of information:
other: literature
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
publication
Title:
Lange's Handbook of Chemistry (15th Edition)
Author:
Dean, J.A.
Year:
1999
Bibliographic source:
McGraw-Hill 1999; Lange's Handbook of Chemistry (15th Edition)

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Tetramethylenediamine
EC Number:
203-782-3
EC Name:
Tetramethylenediamine
Cas Number:
110-60-1
Molecular formula:
C4H12N2
IUPAC Name:
butane-1,4-diamine

Results and discussion

Dissociating properties:
not determined
Dissociation constantopen allclose all
No.:
#1
pKa:
10.8
Temp.:
25 °C
No.:
#2
pKa:
9.35
Temp.:
25 °C

Applicant's summary and conclusion

Conclusions:
The dissociation constant is important as it indicates partitioning behaviour of the substance in the environment and what chemical species are likely to be present in the environment and in vivo.
Executive summary:

The dissociation constant is important as it indicates partitioning behaviour of the substance in the environment and what chemical species are likely to be present in the environment and in vivo.