Registration Dossier

Administrative data

Endpoint:
dissociation constant
Type of information:
other: literature
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
publication
Title:
Lange's Handbook of Chemistry (15th Edition)
Author:
Dean, J.A.
Year:
1999
Bibliographic source:
McGraw-Hill 1999; Lange's Handbook of Chemistry (15th Edition)

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Dissociating properties:
not determined
Dissociation constantopen allclose all
No.:
#1
pKa:
10.8
Temp.:
25 °C
No.:
#2
pKa:
9.35
Temp.:
25 °C

Applicant's summary and conclusion

Conclusions:
The dissociation constant is important as it indicates partitioning behaviour of the substance in the environment and what chemical species are likely to be present in the environment and in vivo.
Executive summary:

The dissociation constant is important as it indicates partitioning behaviour of the substance in the environment and what chemical species are likely to be present in the environment and in vivo.