Registration Dossier

Administrative data

Description of key information

DAB: LD50 (oral) = 749 mg/kw bw
DAB: LD50 (dermal) = 825 mg/kg bw
DAB: LC50 (rat; inhalation) = 1,131 mg/l

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
749 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
1 131 mg/m³

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
825 mg/kg bw

Additional information

All three routes of exposure (oral, dermal and inhalation) lead to classification for acute toxicity.

Justification for classification or non-classification

LD50 (rats, oral) = 740 mg/kg bw; CLP (300 -2000 mg/kg): Acute oral toxicity Category 4; H302 Harmfull if swallowed

LD50(rabbit, dermal) = 825 mg/kg bw; CLP (200 -1000 mg/kg): Acute dermal toxicity Cat. 3; H311 Toxic in contact with skin

LC50(rat, inhalation) = 1.131 mg/l; CLP (0.5 - 2 mg/l, 4h): Acute inhalation toxicity Cat 2; H330 Fatal if inhaled