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Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Hydrolysis
Author:
Sustainability Support Service (Europe) AB - estimated
Year:
2011
Bibliographic source:
Estimation Programs Interface Suite™ United States Environmental Protection Agency, Washington, DC, USA. version 4.1

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modelling database
Principles of method if other than guideline:
AOP Program (v1.92) from EPI Suite estimation database
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
4-nitro-o-xylene
EC Number:
202-761-6
EC Name:
4-nitro-o-xylene
Cas Number:
99-51-4
Molecular formula:
C8H9NO2
IUPAC Name:
4-nitro-o-xylene
Details on test material:
Substance Name : 4-nitro-o-xylene
Molecular Formula : C8H9NO2
Physical state : Liquid
Radiolabelling:
not specified

Study design

Analytical monitoring:
not specified
Estimation method (if used):
AopWin v1.92
Duration of test
Duration:
10.169 d
Temp.:
25

Results and discussion

Transformation products:
not specified
Dissipation DT50 of parent compound
Temp.:
25 °C
DT50:
10.169 d
Type:
other: Estimation
Remarks on result:
other: Hydrolysis rate constant: 1.0519 E-12 cm3/molecule-sec

Applicant's summary and conclusion

Conclusions:
The hydrolysis rate constant of 4-nitro-o-xylene was estimated to be 0.0000000000010519 (1.0519 E-12) cm3/molecule - sec at half life of 10.169 days.
Executive summary:

The Hydrolysis rate constant of 4-nitro-o-xylene is estimated to be 0.0000000000010519 (1.0519 E-12) cm3/molecule-sec. at half life of the 10.169 days.The estimated half life of the substance indicates that the substance is poorly hydrolysable.