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Registration Dossier
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EC number: 202-761-6 | CAS number: 99-51-4
Biodegradation in water and sediment: simulation tests
Administrative data
- Endpoint:
- biodegradation in water and sediment: simulation tests
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Prediction model
- Title:
- Biodegradation in water and sediment by Environmental Science Center’s PBT profiler
- Author:
- Environmental Science Center
- Year:
- 2 010
- Bibliographic source:
- PBT profiler, Office of Chemical Safety and Pollution Prevention , U.S. Environmental Protection Agency; version 1.301
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- PBT profiler database
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-nitro-o-xylene
- EC Number:
- 202-761-6
- EC Name:
- 4-nitro-o-xylene
- Cas Number:
- 99-51-4
- Molecular formula:
- C8H9NO2
- IUPAC Name:
- 4-nitro-o-xylene
- Details on test material:
- Substance Name : 4-nitro-o-xylene
Molecular Formula : C8H9NO2
Physical state : Liquid
Constituent 1
- Radiolabelling:
- not specified
Study design
- Oxygen conditions:
- other: Estimation
- Inoculum or test system:
- not specified
- Parameter followed for biodegradation estimation:
- test mat. analysis
Reference substance
- Reference substance:
- not specified
Results and discussion
Mean total recoveryopen allclose all
- Compartment:
- other: water, material (mass) balance
- % Recovery:
- 19
- Compartment:
- other: sediment, material (mass) balance
- % Recovery:
- 0
% Degradationopen allclose all
- % Degr.:
- 50
- Parameter:
- other: Half life
- Sampling time:
- 38 d
- % Degr.:
- 50
- Parameter:
- other: Half life
- Sampling time:
- 340 d
Half-life of parent compound / 50% disappearance time (DT50)open allclose all
- Compartment:
- water
- DT50:
- 38 d
- Type:
- other: Estimated
- Remarks on result:
- other: Other details not available
- Compartment:
- sediment
- DT50:
- 340 d
- Type:
- other: Estimated
- Remarks on result:
- other: Other details not available
- Transformation products:
- not specified
Applicant's summary and conclusion
- Conclusions:
- Half life period of 4-nitro-o-xylene in water observed 38 days (half-life) while in sediment it is 340 days (half-life). Based on these half life values, it is concluded that 4-nitro-o-xylene is readily biodegradable in water where as it is not likely to biodegrade in sediment.
- Executive summary:
Half life period of 4-nitro-o-xylene in water observed 38 days (half-life) while in sediment it is 340 days (half-life). Based on these half life values, it is concluded that 4-nitro-o-xylene is readily biodegradable in water where as it is not likely to biodegrade in sediment.
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