Registration Dossier
Registration Dossier
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EC number: 202-761-6 | CAS number: 99-51-4
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative databases
- Title:
- Revised Robust Study Summaries and Test Plan for 1,2-dimethyl-4-nitrobenzene
- Author:
- U.S. Environmental Protection Agency
- Year:
- 2 009
- Bibliographic source:
- High Production Volume Challenge Program; Fisher, J., 1975, Toxicity data for o-xylene,4-nitro. Report No. A75-138, American Cyanamid Company, Agricultural Division, Princeton, NJ.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Data is taken from HPV challenge Program.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-nitro-o-xylene
- EC Number:
- 202-761-6
- EC Name:
- 4-nitro-o-xylene
- Cas Number:
- 99-51-4
- Molecular formula:
- C8H9NO2
- IUPAC Name:
- 4-nitro-o-xylene
- Details on test material:
- Substance Name : 4-nitro-o-xylene
Molecular Formula : C8H9NO2
Physical state : Liquid
Constituent 1
Test animals / tissue source
- Species:
- rabbit
Results and discussion
In vivo
Results
- Irritation parameter:
- other:
- Remarks on result:
- other: Not irritating
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The database indicated that 4-nitro-o-xylene is not irritating to eyes of rabbits.
- Executive summary:
The database indicated that 4-nitro-o-xylene is not irritating to eyes of rabbits.
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