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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

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Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB

Farnesene is poorly soluble in water (ECOSAR estimate 11 µg/L) and is not expected to hydrolyse. It is not persistent, as evidenced by up to 61% degradation in 28 days in an OECD 301B study. This is supported by modelled data (EpiSuite v 4.11, BIOWIN v4.10 and BioHCWin v1.01), that predict farnesene will not be readily biodegradable but will be ultimately biodegradable in a period of weeks to months.

Modelled BCF values using CAESAR/Vega 1.0.6 are in the range of 457 - 1479. Based on predicted values of less than 2000 L/kg wet-wt, farnesene is not expected to bioaccumulate.

Farnesene's fully hydrogenated analogue, Farnesane, has been tested in chronic fish and daphnia studies and no toxicity occurred at the limit of water solubility.