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Toxicity to aquatic algae and cyanobacteria

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Description of key information

The effect of the test item on the growth of Pseudokirchneriella subcapitata (freshwater algae) has been investigated over a 72-Hour period and gave the following results (all results in v/v%):
ErC50 (0-72 h) >100% v/v saturated solution
EyC50 (0-72 h) >100% v/v saturated solution
No Observed Effect Concentration based on growth rate: 32% v/v saturated solution
No Observed Effect Concentration based on yield: 32% v/v saturated solution
Lowest Observed effect Concentration based on growth rate: 100% v/v saturated solution
Lowest Observed effect Concentration based on yield: 100% v/v saturated solution
At the limit of solubility there was a small effect on both growth and yield of freshwater algae
Analysis of saturated solution confirmed that the concentration of farnesene present was < LOQ, determined to be 0.13 μg/L.

Key value for chemical safety assessment

Additional information

Farnesene is poorly soluble in water so in a study to investigate the effects of farnesene on freshwater algae, organisms were exposed to dilutions of a saturated solution. Analysis of saturated solution confirmed that the concentration of farnesene present was < LOQ, determined to be 0.13 μg/L.

Results obtained (expressed as % of saturation), are as follows:

ErC50 (0-72 h) >100% v/v saturated solution

EyC50 (0-72 h) >100% v/v saturated solution

No Observed Effect Concentration based on growth rate: 32% v/v saturated solution

No Observed Effect Concentration based on yield: 32% v/v saturated solution

Lowest Observed effect Concentration based on growth rate: 100% v/v saturated solution

Lowest Observed effect Concentration based on yield: 100% v/v saturated solution

These results suggest that at the limit of solubility there is an effect on both growth and yield of algae.