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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

No chronic aquatic toxicity data are available for farnesene.

Based on a read-across study with a structural analogue - farnesane, the NOEC for chronic toxicity of farnesene to fish is predicted to be greater than the limit of water solubility (11 μg/L).

Key value for chemical safety assessment

Additional information

There are no chronic data on the aquatic toxicity of farnesene. In a read-across chronic 'early life' stage study in fathead minnows with farnesane, the NOEC was 66 μg a.i./L. The LOEC and the Maximum Acceptable Toxicant Concentration was estimated to be >66 μg a.i./L, the highest concentration tested. The measured concentrations were greater than the known water solubility of farnesane (0.25 μg/L). Nevertheless, the lack of effects in this study confirm no toxicity at the limit of water solubility.

Based on read-across to the analogue farnesane, it is predicted that farnesene will not cause toxicity to fish at the limit of solubility (11μg/L). Justification for the use of read-across data can be found in section 13 of the dossier.