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EC number: 227-369-2 | CAS number: 5809-08-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- June- December 2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Well conducted study according to OECD guideline, certificate of analysis included in the report.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Version / remarks:
- April 13nd, 2004.
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 2.9
- Temp.:
- 20 °C
- Remarks on result:
- other: pH not reported
- Remarks:
- pH not reported
- Conclusions:
- The average measured log Kow value for 1,1,3,3-tetramethylbutyl hydroperoxide is 2.9.
- Executive summary:
The partition coefficient n-octanol/water (Kow) of 1,1,3,3-tetramethylbutyl hydroperoxide was estimated in dulplicate using the High Performance Liquid Chromatography (HPLC) method. The Kowtest was performed in accordance with the OECD guideline 117. The data on the partition coefficient can be used to predict the adsorption on soil and sediments and for establishing quantitative structure-activity relationships for a wide range of biological effects.
The average measured log Kow value for 1,1,3,3-tetramethylbutyl hydroperoxide is 2.9.
Reference
The average retention times of the reference substances as well as the test substance, corrected for the dead time, are presented in Table IV. The theoretical log Kowvalues of the reference substances were taken from OECD guideline 117.
Table IV: Data retention time and corresponding log k, log Kowdata
Substance |
log Kowtheor. |
Average net |
Average |
Sodium nitrate |
|
0 |
|
Aniline |
0.9 |
0.63 |
-0.28 |
Phenol |
1.5 |
0.70 |
-0.23 |
Methylbenzoate |
2.1 |
1.56 |
0.11 |
Bromobenzene |
3.0 |
3.47 |
0.46 |
Phenantrene |
4.5 |
10.93 |
0.96 |
4,4’-DDT |
6.5 |
27.70 |
1.36 |
1,1,3,3-tetramethylbutyl |
|
2.53 |
0.33 |
Figure 1 in the attachment displays the graph of the theoretical values of log Kowand the average log k of the reference substances.
Figure 2 in the attachment shows an example of a HPLC-chromatogram from the analysis performed according to the test set up.
The average measured log Kowvalue for 1,1,3,3-tetramethylbutyl hydroperoxide was calculated with the retention time from two injections using the calibration plot of log Kowversus log k of the selected reference substances. The average result for log Kowwas determined to be 2.9.
Description of key information
The partition coefficient log Kow value for 1,1,3,3-tetramethylbutyl hydroperoxide is 2.9.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 2.9
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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