Registration Dossier

Diss Factsheets

Environmental fate & pathways

Adsorption / desorption

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Study period:
12 September 2006 - 6 October 2006
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC estimation method
Radiolabelling:
no
Test temperature:
30°C
Details on study design: HPLC method:
Test material (0.1002 g) was diluted to 100 ml with methanol.
The dead time was determined by measuring the retention time of formamide (purity 99.5%, 141 mg/l solution in methanol).
Solutions of reference standards were prepared in methanol.

HPLC System : Agilent Technologies 1100, incorporating autosampler and workstation
Column : Phenosphere Next 5μ CN (250 x 4.6 mm id)
Column temperature : 30ºC
Mobile phase : methanol:water (55:45 v/v)
pH of mobile phase : 7.1, obtained using sodium hydroxide and
phosphoric acid
Flow-rate : 1.0 ml/min
UV detector wavelength : 210 nm
Injection volume : 10 μl
Type:
Koc
Value:
23.5
Type:
log Koc
Value:
1.37
Details on results (HPLC method):
The method guideline states that the measurement of adsorption coefficient should be carried out on substances in their ionised and unionised forms. However, the test material contained no dissociating functional groups which would allow generation of an ionised form within the environmentally relevant pH range valid to the method. Therefore only a single determination was performed, at an approximately neutral pH, on an unionised form of the test material.

Mean retention times (in minutes):
Formamide 3.10
Acetanilide 3.650
Phenol 3.536
Atrazine 3.880
Isoproturon 4.100
Triadimenol 4.441
Linuron 4.490
Naphthalene 4.881
Endosulfan-diol 4.933
α-Endosulfan 9.113
Phenanthrene 6.806
Diclofop-methyl 9.430
DDT 26.554
Sample 1: 3.672
Sample 2: 3.670
Validity criteria fulfilled:
yes
Conclusions:
Based on an adsorption study performed according to the EC guideline and GLP principles, the adsorption coefficient (Koc) of the test material has been determined to be 23.5(log Koc 1.37).

Description of key information

Based on an adsorption study performed according to the EC guideline and GLP principles, the adsorption coefficient (Koc) of the test material has been determined to be 23.5(log Koc 1.37).

Key value for chemical safety assessment

Koc at 20 °C:
23.5

Additional information

Categories Display