Registration Dossier
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EC number: 700-041-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
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- Auto flammability
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- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
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- Nanomaterial pour density
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- Endpoint summary
- Stability
- Biodegradation
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- Environmental data
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- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
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- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
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- Toxicokinetics, metabolism and distribution
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- Additional toxicological data

Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 September 2006 - 6 October 2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Radiolabelling:
- no
- Test temperature:
- 30°C
- Details on study design: HPLC method:
- Test material (0.1002 g) was diluted to 100 ml with methanol.
The dead time was determined by measuring the retention time of formamide (purity 99.5%, 141 mg/l solution in methanol).
Solutions of reference standards were prepared in methanol.
HPLC System : Agilent Technologies 1100, incorporating autosampler and workstation
Column : Phenosphere Next 5μ CN (250 x 4.6 mm id)
Column temperature : 30ºC
Mobile phase : methanol:water (55:45 v/v)
pH of mobile phase : 7.1, obtained using sodium hydroxide and
phosphoric acid
Flow-rate : 1.0 ml/min
UV detector wavelength : 210 nm
Injection volume : 10 μl - Type:
- Koc
- Value:
- 23.5
- Type:
- log Koc
- Value:
- 1.37
- Details on results (HPLC method):
- The method guideline states that the measurement of adsorption coefficient should be carried out on substances in their ionised and unionised forms. However, the test material contained no dissociating functional groups which would allow generation of an ionised form within the environmentally relevant pH range valid to the method. Therefore only a single determination was performed, at an approximately neutral pH, on an unionised form of the test material.
Mean retention times (in minutes):
Formamide 3.10
Acetanilide 3.650
Phenol 3.536
Atrazine 3.880
Isoproturon 4.100
Triadimenol 4.441
Linuron 4.490
Naphthalene 4.881
Endosulfan-diol 4.933
α-Endosulfan 9.113
Phenanthrene 6.806
Diclofop-methyl 9.430
DDT 26.554
Sample 1: 3.672
Sample 2: 3.670 - Validity criteria fulfilled:
- yes
- Conclusions:
- Based on an adsorption study performed according to the EC guideline and GLP principles, the adsorption coefficient (Koc) of the test material has been determined to be 23.5(log Koc 1.37).
Reference
Description of key information
Based on an adsorption study performed according to the EC guideline and GLP principles, the adsorption coefficient (Koc) of the test material has been determined to be 23.5(log Koc 1.37).
Key value for chemical safety assessment
- Koc at 20 °C:
- 23.5
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