Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- not specified
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Halohydrin dehalogenase
- Cas Number:
- 132421-41-1
- IUPAC Name:
- Halohydrin dehalogenase
- Test material form:
- solid
- Details on test material:
- Lot number PF 791
Constituent 1
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- <= 0
- Temp.:
- 23 °C
- Remarks on result:
- other: Since thesubstance does not dissolve in octanol, the partitioncoefficient is not reportable
- Remarks:
- . No data availble on the pH
- Details on results:
- There was no solubility in the octanol phase at 23 °C and therefore no reportable value is available.
Applicant's summary and conclusion
- Conclusions:
- The partitioning coefficient was set to be ≤ 0, due to the fact that no substance was disolved in octanol.
- Executive summary:
A study on CDX-403 was performed to determine the partition coefficient of the test substance, halohydrin dehalogenase enzyme, according to OECD Method 107. There was no solubility in the octanol phase at 23 °C and therefore no value is available. The partitioning coefficient was set to ≤ 0.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
