Registration Dossier
Registration Dossier
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EC number: 207-325-9 | CAS number: 462-34-0
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Additional information
BASF (1995) reported an in vivo skin irritation study using rabbits. Undiluted borfluorid tetrahydrofuran was tested for 3 minutes and 1 hour under semiocclusive conditions. Occurring erythema (score 0.2) after 3 min treatment were fully reversible after 72 h. The average score for irritation could not be calculated after 1-hour application (visual necrosis, hence resulting study termination 24 hours after removal of the test patches). The necrotic changes of the skin were assessed by macroscopic pathology indicating full-thickness necrosis.
As the product corrodes the skin, it can be expected to have a similar effect on the eyes, also.
Justification for classification or non-classification
Classification proposal: C; R34(EU); Skin Corr. 1B - H 314 (GHS).
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