Registration Dossier
Registration Dossier
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EC number: 207-325-9 | CAS number: 462-34-0
Biodegradation in soil
Administrative data
- Endpoint:
- biodegradation in soil
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Study uses unrealistic amounts of tetrahydrofuran that are unlikely to be present in the environment. The test material used was a combination of tetrahydrofuran and 1,4-dioxane.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Biodegradation in soil microcosms
- GLP compliance:
- not specified
- Test type:
- laboratory
Test material
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- Cas Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- tetrahydrofuran
- Reference substance name:
- 1,4-dioxane
- EC Number:
- 204-661-8
- EC Name:
- 1,4-dioxane
- Cas Number:
- 123-91-1
- IUPAC Name:
- 1,4-dioxane
- Details on test material:
- Tetrahydrofuran and 1,4-dioxane (purities of either substance were not given).
Constituent 1
Constituent 2
- Radiolabelling:
- no
Study design
- Oxygen conditions:
- aerobic
- Soil classification:
- not specified
- Details on soil characteristics:
- Soil used was previously exposed to 1,4-dioxane
Duration of test (contact time)
- Soil No.:
- #1
- Duration:
- 100 d
Initial test substance concentration
- Soil No.:
- #1
- Initial conc.:
- 200 other: mg/l
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on experimental conditions:
- Study was conducted at 35 °C in the dark.
Results and discussion
% Degradation
- Soil No.:
- #1
- % Degr.:
- 100
- Parameter:
- test mat. analysis
- Sampling time:
- 100 d
- Transformation products:
- not specified
- Evaporation of parent compound:
- not specified
- Volatile metabolites:
- not specified
- Residues:
- not specified
Applicant's summary and conclusion
- Conclusions:
- Under the conditions of this study, complete biodegradation of tetrahydrofuran and 1,4-dioxane occurs under enhanced conditions (35 °C and addition of nitrogen, phosphorus and other trace elements). Under ambient conditions, there was no biodegradation of tetrahydrofuran and 1,4-dioxane.
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