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Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Four key acute aquatic toxicity studies have been performed for BMS 296796-02. All studies were assigned reliability rating of 1 (reliable without restriction). All results were considered valid and according to GLP. Based on the following results, the test material does not meet the critieria for environmental classification and labeling according to the EU regulations.

Short-term toxicity to fish: The acute toxicity of the test material to the freshwater fish rainbow trout (Oncorhynchus mykiss) has been investigated and gave a 96-Hour LCso of greater than 100 mg/L. Correspondingly the No Observed Effect Concentration was 100 mg/L.

Short -term toxicity to daphnia magna: The acute toxicity of the test material to the freshwater invertebrate Daphnia magna has been investigated and gave a 48-Hour ECS0 of greater than 100 mg/L. Correspondingly the No Observed Effect Concentration was 100 mg/L.

Toxicity to aquatic algae: The effect of the test material on the growth of Scenedesmus subspicatus has been investigated over a 72-Hour period and gave an EbC50 (72 h) value of 60 mg/L. At the maximum concentration tested (100 mg/L) exposure to the test material resulted in 30% inhibition of the 0 -72 hour growth rate and hence the ErC5O (0 -72 h) was greater than 100 mg/L. It was considered unnecessary and unrealistic to test at concentrations in excess of 100 mg/L. The No Observed Effect Concentration at 72 hours was 25 mg/L.

From the data both the growth (r) and the biomass (b) of Scenedesmus subspicatus (CCAP 276120) were affected by the presence of the test material over the 72-Hour exposure period. Based on the geometric mean measured test concentrations the EbC50 (72 h) value was 49 mg/L and the ErC5O (0 -72 h) value was greater than 82 mg/L . The No Observed Effect Concentration at 72 hours was 16 mg/L.

Toxicity to microorganism sludge respiration: The effect of the test material on the respiration of activated sewage sludge gave a 3-Hour EC50 of 2800 mg/L. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 1000 mg/L.