Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
April 2005 -June 2005
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted in 2005 according to Method A4 of the Commission Directive 92/69/EEC and in accordance with GLP. Study material is well characterized.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005
Report date:
2005

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: vapour pressure balance

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
445-910-2
EC Name:
-
Cas Number:
649761-22-8
Molecular formula:
Hill formula: C24 H32 N2 O7 Si CAS formula: C15 H20 O3 Si . C9 H12 N2 O4
IUPAC Name:
(1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate

Results and discussion

Vapour pressure
Temp.:
25 °C
Vapour pressure:
0 Pa

Any other information on results incl. tables

A sequence of runs was started after a sample of test material had been under vacuum for approximately 24.5 hours. Temperature and pressure readings were taken between 114 and 124oC with a one hour dwell at 114oC between runs.

Summary of Results

Run Log10 [Vp(25oC)] 
 1 -6.992 
 2 -6.728
 3 -6.685 
 4 -6.542 
 5 -6.478 
 6 -6.593
 7  -6.596
Mean -6.659   
Vapour Pressure  2.2 x 10 -7 Pa   

Applicant's summary and conclusion

Conclusions:
The Vapour Pressure of the test material was determined to be 0.00000022 Pa at 25 degrees celsius
Executive summary:

The Vapour Pressure of the test material was determined to be 2.2 x 10-7 Pa at 25oC