Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted in 2003 according to Method A6 of the Commission Directive 92/69/EEC and in accordance with GLP. Study material is well characterized.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2003
Report Date:
2003

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Commission Directive 92/69/EEC, A6 (flask method).
Deviations:
no
GLP compliance:
yes
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Water solubility
Water solubility:
11.2 mg/L
Temp.:
20 °C
pH:
6.1
Details on results:
The solubility of the two dissociated components (i.e. acid component and the amine component) in water was determined to be 11.2 g/l each. Hence, water solubility of the whole substance is 11.2 g/l.

Any other information on results incl. tables

Results for Acid Component

 Sample Number  Time Shaken at ~30oC (hours)  Time Equilibrated at 20oC (hours)  Concentration (g/l)  Solution pH
1 24 24  10.8  6.1 
48  24  11.0  6.1 
72  24  11.8  6.1 

Mean concentration: 11.2g/l at 20.0 + 0.5 oC

Range:                     10.8 to 11.8 g/l

Results for Amine Component

 Sample Number  Time Shaken at ~30oC (hours)  Time Equilibrated at 20oC (hours)  Concentration (g/l)  Solution pH
1 24 24  10.9  6.1 
48  24  11.0  6.1 
72  24  11.8  6.1 

Mean concentration: 11.2g/l at 20.0 + 0.5 oC

Range:                     10.9 to 11.8 g/l

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The solubility of the two dissociated components (i.e. acid component and the amine component) in water was determined to be 11.2 g/l each. Hence, water solubility of the whole substance is 11.2 g/l.
Executive summary:

The substance has been shown to be very soluble in water.