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Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014
Report Date:
2014

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Fraunhofer ITEM procedure (SEM; size distribution analysis)
Version / remarks:
SEM analysis done
Deviations:
no
Principles of method if other than guideline:
Light microscopy measurement (digital microscope consisting of the main unit VHX-1000 D, the camera unit VHX-1100 and a zoom objective VH-Z250R; Keyence Corp., Osaka, Japan) - 148 particles were measured for the diameter
GLP compliance:
yes
Type of method:
other: SEM
Remarks:
none
Type of distribution:
counted distribution

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: particulates

Results and discussion

Remarks on result:
other: D10: 3.15 µm
Particle sizeopen allclose all
Key result
Percentile:
D50
Remarks on result:
other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
Key result
Percentile:
D50
Mean:
> 9.68 - < 9.7 µm
Remarks on result:
other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
Remarks:
none
Key result
Percentile:
D90
Mean:
> 29.51 - < 29.53 µm
Remarks on result:
other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
Remarks:
none
Particle size distribution at different passages
Remarks on result:
other: see 'Particle size'
Remarks:
SEM method (Fraunhofer ITEM); see 'Any other information on results' below

Any other information on results incl. tables

Number-weighted diameter of the test item: Geometric mean = 9.50; calculated aerodynamic diameter: 10.2 µm

Applicant's summary and conclusion

Conclusions:
Geometric mean: 9.50 µm; calculated aerodynamic diameter: 10.2 µm --> Test item is practically not respirable.