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EC number: 939-707-2
CAS number: -
LC: Loss of corneal tissue
MV: Marginal vascularization of the cornea
PC: Pupil contracted
RE: Small Retractions in the eyelids
calculated for each animal over 24, 48 and 72 hours were 1.0, 1.0 and
1.0 for corneal opacity; 0.33, 0.0 and 0.0 for iris lesions; 2.0, 2.0
and 2.0 for redness of the conjunctiva and 0.66, 1.0 and 0.0 for
substance has been tested for eye irritation in rabbits, according to
O.E.C.D. guideline Nb.405. 0.1 ml of the test article was instilled in
the eye of White rabbits (3 animals). Animals were then observed for 21
days. Irritation was scored.
substance was found to be severely irritating to the eye in the rabbit.
Persistence of eye damages at the end of the observation period (21
days) was observed. Mean scores calculated for each animal over 24, 48
and 72 hours were 1.0, 1.0 and 1.0 for corneal opacity; 0.33, 0.0 and
0.0 for iris lesions; 2.0, 2.0 and 2.0 for redness of the conjunctiva
and 0.66, 1.0 and 0.0 for chemosis.
experimental conditions of this study, the test item was found severely
irritating to the eye of rabbit. Based on these results, the test item
reaction product of naphthalene, butanol, sulfonated and neutralized by
caustic soda is classified Xi, R 41, risk of serious damage to eyes,
according to Annex VI of the Directive 67/548/CEE and Eye Damage, Cat 1,
H318 according to EU Regulation 1272/2008 (CLP), considering the
persistence of eyes damages at the end of the observation period (21
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