Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 939-707-2
CAS number: -
LC: Loss of corneal tissue
MV: Marginal vascularization of the cornea
PC: Pupil contracted
RE: Small Retractions in the eyelids
calculated for each animal over 24, 48 and 72 hours were 1.0, 1.0 and
1.0 for corneal opacity; 0.33, 0.0 and 0.0 for iris lesions; 2.0, 2.0
and 2.0 for redness of the conjunctiva and 0.66, 1.0 and 0.0 for
substance has been tested for eye irritation in rabbits, according to
O.E.C.D. guideline Nb.405. 0.1 ml of the test article was instilled in
the eye of White rabbits (3 animals). Animals were then observed for 21
days. Irritation was scored.
substance was found to be severely irritating to the eye in the rabbit.
Persistence of eye damages at the end of the observation period (21
days) was observed. Mean scores calculated for each animal over 24, 48
and 72 hours were 1.0, 1.0 and 1.0 for corneal opacity; 0.33, 0.0 and
0.0 for iris lesions; 2.0, 2.0 and 2.0 for redness of the conjunctiva
and 0.66, 1.0 and 0.0 for chemosis.
experimental conditions of this study, the test item was found severely
irritating to the eye of rabbit. Based on these results, the test item
reaction product of naphthalene, butanol, sulfonated and neutralized by
caustic soda is classified Xi, R 41, risk of serious damage to eyes,
according to Annex VI of the Directive 67/548/CEE and Eye Damage, Cat 1,
H318 according to EU Regulation 1272/2008 (CLP), considering the
persistence of eyes damages at the end of the observation period (21
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again