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EC number: 939-707-2 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The 3-hour NOEC for total respiration for Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda to activated sludge microorganisms was 0.16 mg/L.
The 3-hour NOEC for heterotrophic respiration for Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda to activated sludge microorganisms was 0.05 mg/L.
The 3-hour NOEC for nitrification respiration for Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda to activated sludge microorganisms was 1.64 mg/L.
The 3-hour EC50 for Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda to activated sludge microorganisms was determined to be greater than the highest level tested, 5.2 mg/L.
By analogy, the 3-hour NOEC for Reaction product of naphthalene, butanol, sulfonated and neutralized by caustic soda was assumed to be the same value (NOEC = 1.64 mg/L)
Key value for chemical safety assessment
Additional information
The toxicity to microorganisms of Reaction product of naphthalene, butanol, sulfonated and neutralized by caustic soda is determined by a read-across approach based on analogue substance Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda.
A GLP-compliant study (KJ. Muddiman, 2013), scored as Klimisch 2 and flagged as a key study, is available on Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda.
The following results were determined:
| NOEC (mg/L) | LOEC (mg/L) | EC50 (mg/L) | |
| Total respiration | 0.16 | 0.51 | > 5.2 |
| Heterotrophic respiration | 0.05 | 0.16 | > 5.2 |
| Nitrification respiration | 1.64 | 5.2 | > 5.2 |
The overall NOAEC determined during this study was 0.05 mg/L, based on heterotrophic respiration. The overall EC50 was determined to be greater than the highest level tested, 5.2 mg/L.
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