Registration Dossier
Registration Dossier
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EC number: 200-554-5 | CAS number: 63-05-8
Auto flammability
Administrative data
Link to relevant study record(s)
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08 to 16 Aug 2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.16 (Relative Self-Ignition Temperature for Solids)
- Deviations:
- no
- GLP compliance:
- yes
- Key result
- Remarks on result:
- no self ignition observed under the test conditions
- Conclusions:
- No endothermic or exothermic effect of the test substance was observed between 20°C and 170°C. It demonstrates that Androst-4-ene-3,17-dione is not self-ignitable.
- Executive summary:
The self-ignition temperature of Androst-4-ene-3,17-dione was determined using a temperature programmed laboratory oven, a stainless steel wire mesh cube, NiCr/NiAl thermocouples and a temperature recording device. Based on the results obtained the test substance is considered 'not self-ignitable'.
Reference
No endothermic or exothermic effect of the test substance was observed between 20°C and 170°C.
Validity criteria for the measurement of the self-ignition temperature:
| Target condition according to guideline: | Actual condition according to the study: | Validity criteria met: |
The temperatures of the oven and sample are continuously recorded while the temperature of the oven is increased to 400 °C, or to the melting point if lower, at a rate of 0.5 °C /min. | The oven was heated from 22°C to 400°C at a rate of 0.5°C/minute. | Yes |
| The results of measurement including the temperature/ time curve shall be stated. | Are stated- | Yes |
Description of key information
No endothermic or exothermic effect of the test substance was observed between 20 °C and 170 °C.
Key value for chemical safety assessment
Additional information
The result demonstrates that Androst-4-ene-3,17-dione is not self-ignitable.
Two studies are available for this endpoint. The GLP study with a reliability of 1 was taken as key study.
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