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EC number: 941-793-1
CAS number: -
In an acute dermal toxicity study (OECD
402), 5 young adult Wistar rats of both sexes were dermally exposed to
doses of 2000 mg/kg and 500 mg/kg bw of 2-Propyn-1-ol, compd. with
methyloxirane to the clipped skin and covered by semi-occlusive
dressing for 24 hours under GLP conditions. The application area
comprised at least 10% of the total body surface area.
The animals were observed for 14 days,
where no mortality occurred and no other signs of systemic toxicity were
Accordingly, the acute dermal median
lethal dose (LD50)
was determined to be LD50,
dermal, rat > 2000 mg/kg bw and
no classification concerning GHS (EU) is recommended. (BASF
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