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EC number: 941-793-1
CAS number: 32199-97-6
LD50 male animals: ca. 464 mg/kg; LD50 female animals > 464 < 2150 mg/kg
ln principle, the methods described in OECD Guideline 401 were
used without GLP compliance.
5 rats per sex and dose were treated simultaneously with
concentrations of 5000,
2150, 464 and 215 mg/Kgby gavage with preparations of the
test substance in water as vehicle.
Group-wise documentation of clinical signs was performed over a
14- day study period, where clinical signs and mortality were documented
at least once daily. Mortality was observed among the high doses in both
sexes after 24 hours: 5000 mg/kg (5/5) and 2150 mg/kg (5/5). At 465
mg/kg 2 of 5 male animals died.
On the basis of the observed lethality, the LD50 value was
estimated to be > 464 <2150 mg/kg bw for female and about 464 mg/kg bw
for male. As a conseqence of it, the test substance should be classified
as acute oral toxicity category 4 (GHS). (BASF, 1987)
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