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EC number: 941-793-1
CAS number: 32199-97-6
Neither the the preincubation test nor the
standard plate test with or without S-9 mix increased the number of his+
revertants in any of the tested bacteria strains.
substance 2-Propyn-1-ol, compd. with methyloxirane was
tested for its mutagenic potential
based on the ability to induce back mutations in
selected loci in several strains of Salmonella typhimurium
1535, TA 100, TA 1537, TA 98) in
the Ames test with a concentration range of 20 µg - 5000 µg/plate with
and without metabolic activation according to OECD 471 under GLP
No bacteriotoxic effect was observed.
increase in the number of his+ revertants was not observed
both in the standard plate test and in the preincubation
test either without S-9 mix or after the
of a metabolizing system.
to the results of the present study, the test substance
2-Propyn-1-ol, compd. with methyloxirane
is not mutagenic in the Ames test
under the experimental conditions chosen here.(BASF 1995)
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