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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

Under the conditions of the present key study, the 48h EC50 for D. magna exposed to cyclohexylbenzene is 0.37 mg/l.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.37 mg/L

Additional information

There are two studies available on short term toxicity of cyclohexylbenzene to D. magna.

The study of Heidolph et al. (1983) was performed according to the EPA 660/3-75-009 guideline without GLP conditions. The acute toxicity of cyclohexylbenzene to D. magna was assessed during a 48-hour static test. The 48 -hour EC50 value was calculated as 0.703 mg/L and the NOEC was determined to be 0.56 mg/L.

The second study is performed by the Ministry of Health and Environment of Japan. Also in this study, the acute toxicity of cyclohexylbenzene to Daphnia magna was assessed during a 48-hour static test. The 48 -hour EC50 value was calculated as 0.37 mg/L. The study is written in Japanese but the results and main information on methodology are given in table format.

Based on the precautionary principle, the study by the Japanese ministry of environment is considered to be the key study. An EC50 (48h) of 0.37 mg/L is therefore taken into account for the risk assessment.