Registration Dossier
Registration Dossier
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EC number: 255-272-5 | CAS number: 41233-93-6
Carcinogenicity
Administrative data
Description of key information
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
The test substance hydrolyses rapidly in the presence of water. Therefore, the hydrolysis products are considered to be relevant for classification according to CLP regulation (EC) No 1272 /2008.
For the hydrolysis products potassium hydroxide (CAS No. 1310-58-3) and 2-methylbutan-2-ol (CAS No. 75-85-4) disseminated dossiers are available on the homepage of ECHA. The hydrolysis products are not classified for carcinogenicity according to CLP regulation Annex VI and according to the self-classification of the disseminated dossiers. Due to this, a classification of the test substance as carcinogenic according to CLP regulation is also not applicable.
Additional information
No data are available on the carcinogenicity of potassium 2-methylbutan-2-olate. The test substance is used as transported intermediate in a closed system.According to the REACh regulation (EC) No 1907/2006, Article 18.2 further testing is not required for this tonnage band and no evidence for carcinogenicity is available. Under the strictly controlled conditions repeated exposure of workers is not expected. Due to the corrosive nature of the test substance, is it unlikely that repeated human exposure occurs under normal handling and use conditions.
Furthermore, the test substance is classified as corrosive to skin according to the CLP regulation (EC) No 1272/2008. In vivo testing with corrosive substances at concentrations causing corrosivity shall be avoided, as pointed out in the introductions to Annexes VII-X of the REACh Regulation (EC) No 1907/2006.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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